The endocannabinoid system works in many regulatory functions of the body both in health and disease. Recent studies have intriguingly suggested the existence of a functional ECS in the skin contributes to various biological processes In that it seems to control the proper and well-balanced increase in number of cells, development of specialized features, survival,and immune competence and/or tolerance, of skin cells.
The skin and its appendages acts as a barrier against constant environmental challenges. However, what is interesting is that the skin with its hair and pores also acts as ‘active’ neuro-immuno-endocrine organs which means it contributes to our overall health. A well functioning skin helps with the proper functioning of other systems in the body. Considering that the skin is the main agent in the production of vitamin D we can see how its health can influence the health of various other systems in the body.
What is exciting to note is that modulating the activity of the endocannabinoid system hold many therapeutic benefits for a multitude of diseases and health conditions affecting humans, such as inflammation, neuro-degenerative conditions, gastrointestinal issues, liver diseases, cardiovascular disorders and obesity, ischemia (nadequate blood supply to an organ), cancer and chronic pain. The point here is that health starts at the skin and then moves inward. With CBD products we can advance the modulation of the endocannabinoid system.
How CBD oil reduces various types of acne lies in its ability to adjust how the body creates sebum. Sebum is the waxy or oily substance the skin makes. Sebum helps to protect the skin from the outside world. However, when it mixes with dead skin cells, dirt, or pollutants these can get trapped inside a pore. This clogged pore is the cause of acne.
Obviously there are many factors that influence acne, such as excess sebum production, hormonal imbalances, and genetics, diet, and stress. Some medicines can also cause a flare up in acne
CBD's role in preventing acne lies in its ability to prevent over creation of sebum. CBD oil also triggers an anti-inflammatory reaction in the cells and prevents inflammatory cytokines (a broad and loose category of small proteins important in cell signaling) from activating. this is important because cytokines can trigger acne.
CBD can also help manage other skin conditions:
- Eczema and psoriasis
- Sensitive skin
- Aging and wrinkles
- slow the growth of skin cancer
We will look at these conditions in separate articles
For skin disease a topical application of CBD in the form of a cream or balm plus ingesting cbd in the form of a CBD Oil gives the best results. Some success has been seen from just the topical application, but we see better result from a combination of methods.
- Cannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes
- A novel control of human keratin expression: cannabinoid receptor 1-mediated signaling down-regulates the expression of keratins K6 and K16 in human keratinocytes in vitro and in situ
- Efficacy and Tolerance of the Cream Containing Structured Physiological Lipids With Endocannabinoids in the Treatment of Uremic Pruritus: A Preliminary Study
- An Update on Safety and Side Effects of Cannabidiol: A Review of Clinical Data and Relevant Animal Studies